智鼠故事 
Slc7a11-KO 基因敲除小鼠
复苏/繁育服务
产品名称
Slc7a11-KO 基因敲除小鼠
产品编号
S-KO-08541
品系全称
C57BL/6JCya-Slc7a11em1/Cya
品系背景
C57BL/6JCya
品系编号
KOCMP-26570-Slc7a11-B6J-VA
品系状态
使用本品系发表的文献需注明： Slc7a11-KO 基因敲除小鼠 mice (Strain S-KO-08541) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因全称
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
基因别称
sut，xCT，9930009M05Rik
染色体号
Chr 3 (Mouse)
NCBI ID
转录本 ID
NCBI: NM_011990 | Ensembl: ENSMUST00000029297
修饰方式
全身性基因敲除
靶向范围
Exon 3
敲除长度
~0.1 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:1347355Homozygous mutant mice show a reduction in yellow pigment resulting in dilution of agouti; only pinna hairs are affected in nonagouti mice. Mice homozygous for an ENU-induced allele exhibit decreased survival of LPS-induced macrophages and increased incidence of chemically-induced tumors.
发表文献
Cell Death Discovery
2024-09-30
Unveiling the crucial role of ferroptosis in host resistance to streptococcus agalactiae infection
Redox Biology
2024-04-16
SLC7A11-ROS/αKG-AMPK axis regulates liver inflammation through mitophagy and impairs liver fibrosis and NASH progression
Advanced Science
2022-11-27
Targeted xCT-mediated Ferroptosis and Protumoral Polarization of Macrophages Is Effective against HCC and Enhances the Efficacy of the Anti-PD-1/L1 Response
1
发表文献
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